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Are You Going to Use Finasteride for Hair Loss? Read This First

Sold in the market under the brand names Propecia and Proscar, finasteride is a medication that is intended to treat people who are suffering from hair loss.  In the early days, finasteride was just like other medications that were originally used to treat benign prostatic hypertrophy and prostate cancer. It turns out that patients who took finasteride for their prostate-related issues had experienced great results with it, along with a surprising bonus, and that is, the growth of hair.

Finasteride actually works by means of inhibiting or stopping type II 5-alpha reductase, the enzyme responsible for converting the hormone testosterone into dihydrotestosterone (DHT).  DHT, in turn, is the one responsible for losing one’s hair, resulting to baldness if not remedied.  Thus, simply put, the action of finasteride is to prevent the conversion of testosterone into DHT, and the end result would be the prevention of hair loss. This “favorable side effect” of preventing hair loss and promoting growth of new hair by finasteride is what made it famous in the pharmaceutical world, not by its primary use which is for treating benign prostatic hypertrophy and other prostate-related ailments. Read more…

What's in the news: May 29 -- Chalk River closed for 3 months or longer

Chalk River shutdown to last "at least three months"
Revised upwards from earlier estimates, the Chalk River shutdown will last "at least three months," said the chief nuclear officer of Atomic Energy of Canada Limited (AECL). Nuclear medicine experts in Canada and the US have expressed grave concerns about what now appears to be an inevitable shortage of radioisotopes, which are needed for the contrast materials used in diagnostic imaging. [Toronto Star]

Asked by a Globe and Mail reporter whether the nuclear plant might be shut down indefinitely, Natural Resources Minister Lisa Raitt said, "The answer is, we don't know." [Globe and Mail]

Health Minister Leona Aglukkaq said she is working to coordinate with foreign providers but, in a shockingly bad stroke of luck, three of the four other reactors worldwide that produce similar radioisotopes are also shut down at the moment. [CBC News]

Linda Keen, the former president of the Canadian Nuclear Safety Commission, said the current crisis is even worse than the 2007 one that got her fired. (In 2007, Ms Keen required Chalk River to shut down for safety repairs, but when a radioisotope shortage appeared to be imminent the government convened to pass emergency legislation overruling her, leading to her dismissal.) [Toronto Star]

Quebec pathologists raise spectre of breast cancer testing errors
A small study by the Quebec association of pathologists revealed disturbingly high rates of errors, prompting calls for mass re-testing. "There are thousands of patients who have cancer and who received treatment. Did they get the good treatment?” said Health Minister Dr Yves Bolduc. “Some people perhaps didn't get treatment and should have received it." Quebec does not have a quality-assurance process to verify its pathology results. [Globe and Mail]

After years of scrutiny and painful discoveries of wrongdoing and cover-ups of breast-cancer pathology test errors in Newfoundland, the news that Quebec might have some of the same problems distressed many people. In a release issued Friday, the Canadian Breast Cancer Network called for "huge system change." "Given the errors in Newfoundland and Labrador and now in Quebec, it is evident that this is not a regional problem – it is a national one," said CBCN president Diana Ermel. "CBCN therefore calls for urgent action to implement systemic changes, with the establishment of uniform standards in Canada as a necessary first step to begin to restore confidence in the medical system in this country by women diagnosed with breast cancer and their families. We know that Canadian pathologists are working diligently to advance national laboratory standards and we applaud their efforts."

ADQ health critic Eric Caire blamed the governing Liberals for dragging their feet on responding to the current allegations and for failing to prevent the errors by fixing the system sooner. [ADQ news release]

Hugh Short attempted murder charge dropped
Canadian officials have dropped a charge of attempted murder against James Kopp in the case of the 1995 shooting of Ancaster, Ontario, physician and abortion provider Hugh Short. Mr Kopp is currently serving a life sentence after being convicted of killing an abortion provider in New York. [UPI]

Need bariatric surgery? Get in line
A new national survey measured bariatric surgery wait times across Canada and found the average wait time is five years. "The waiting times for bariatric surgery are the longest of any surgically treated condition," concluded study authors Drs Nicolas Christou and Evangelos Efthimiou. "Given the significant reduction in the relative risk of death with bariatric surgery (40%–89% depending on the study), the current waiting times for the procedure in Canada are unacceptable." [Canadian Journal of Surgery (PDF)]

Earlier this week, the government of Ontario announced it will spend $12.6 million over the next three years to increase the province's capacity to provide patients with bariatric surgery by 750% and to fund obesity research and prevention projects. [Ontario Ministry of Health and Long Term Care news release]

More wait times woes
Speaking of wait times, here's an incredible story: Adult thalassemia and sickle cell disease patients in Toronto can't access adult services at Toronto General Hospital until one of the 99 current patients dies and a spot opens up. 150 patients are left without help beyond the blood transfusions they require. [Anemia Institute for Research and Education news release]

Pay parity
Higher pay for specialists in Quebec is unfair, charged the provincial association of general practitioners. "Numbers don't lie: general practitioners' compensation is not competitive," said Dr Louis Godin, the president of the Fédération des médecins omnipractitiens du Québec, in a release. "The ever-widening compensation gap between general practitioners and medical specialists in Quebec is becoming disproportionately lopsided and unjustifiable when one considers the current crisis in family medicine." [FMOQ news release]

Wonky news
The latest Health Wonk Review is up. [Boston Health News]

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  1. sharon31 May, 2009 8:47 AM

    RE: the isotope shortage

    I think this is an "excellent " educational read:

    I still maintain there are "marketplace" leaks muddying the waters as some of the private sector partners "appear" to be acting like a monopoly..

    ...hmmm...maybe the flow chart shown in this document should have more partners in the horizontal lines....

    ....hmmm....... maybe a "core-shell" flow chart could be considered to bypass communication /service obstacles...... hmmmmmm