The reproductive system of both males and females are specialized in function and that they only work with the specific gender they are given to. While the female reproductive system is more complex as it houses the environment a fertilized egg will grow into, the male reproductive system is in no way a simple one as well. Perhaps, the most visible difference of the male reproductive system to that of the females is that the male have an external protruding structure. This external structure is situated outside of the body and consists of the penis, the testicles, and the scrotum. Read more…
When to beware
As all meds do, mythylnaltrexone bromide (Relistor) has its share of possible side effects, the most common being dizziness, flatulence, mild diarrhea, nausea, stomach pain, vomiting, and hyperhidrosis. Severe reactions include a serious case of any already mentioned, or allergic reactions.
Today, Health Canada and Wyeth Canada added a new possible adverse reaction to the list: a heightened risk of gastrointestinal perforation, especially in those with GI cancers and other conditions that could weaken the gastrointestinal wall.
When Relistor came onto the scene – it was approved by Health Canada on March 28, 2008 – it relieved opioid-induced constipation in palliative-care patients with incurable cancers, end-stage COPD from emphysema, heart failure, Alzheimer’s disease, and so on, when other laxative therapies could not – in under 30 minutes. Administered by subcutaneous injection, it blocks opioids from entering cells, allowing bowels to revert to normal function, while not interfering with the opioid’s ability to relieve pain.
The current warning advises discontinuing Relistor and seeking professional help if severe, persistent symptoms like abdominal pain intensified by movement, nausea and vomiting -- possibly accompanied by fever and chills – worsen, as these can be signs of GI perforation.
It makes one wonder, though, if the original studies on this drug should have lasted a wee bit longer than four months.
Posted by David Elkins and others at 6:08 PM
Labels: Health Canada warning, mythylnaltrexone bromide, Relistor, Wyeth Canada